17 April 2020
Leeds, UK, 4D pharma plc (AIM: DDDD), a pharmaceutical company leading the development of Live Biotherapeutics, today announces that Prof. Axel Glasmacher, MD, has been appointed as Non-Executive Chairperson of the Board, with immediate effect.
Prof. Glasmacher joined the Board of 4D pharma as a Non-Executive Director in January 2019. Previously, he was Senior Vice President and Head of Global Clinical Research & Development, Hematology Oncology at Celgene, where he worked in various global roles for more than 10 years. His work at Celgene led to the approvals of Revlimid®, Idhifa®, and Vidaza® (haematological cancers). He also worked on the anti-PD-L1 checkpoint inhibitor Imfinzi® (durvalumab). Prior to Celgene, Professor Glasmacher worked within the fields of hematology-oncology at the University Hospital in Bonn.
David Norwood, the current Non-Executive Chairperson, will concurrently step down from this role but remains as a Non-Executive Director of 4D.
“4D is a company that has done excellent scientific and clinical work and is looking forward to important data readouts in the near future,” said Prof. Glasmacher. “I am honored to work with investors, the Board and the team at 4D to bring Live Biotherapeutic agents to patients as soon as possible.”
“I am very pleased to report that Axel has taken up the position of Chairperson,” said Duncan Peyton, CEO, 4D pharma. “Since joining 4D’s Board of Directors, Axel has made a significant contribution to the development of the Company’s strategy. In addition, his expertise and track record in oncology are highly complementary to our focus going forward. I would also like to thank Dave Norwood for his significant contribution to 4D as Chairperson, a role he has held since the formation of the Company, and I look forward to continuing to work with him in his role as a Non-Executive Director.”
Founded in February 2014, 4D pharma is a world leader in the development of Live Biotherapeutics, a novel and emerging class of drugs, defined by the FDA as biological products that contain a live organism, such as a bacterium, that is applicable to the prevention, treatment or cure of a disease. 4D has developed a proprietary platform, MicroRx®, that rationally identifies Live Biotherapeutics based on a deep understanding of function and mechanism.
4D's Live Biotherapeutic Products are orally delivered single strains of bacteria that are naturally found in the healthy human gut. The Company has five clinical studies in progress, namely a Phase II clinical study of BLAUTIX® in Irritable Bowel Syndrome (IBS), a Phase I/II study of MRx0518 in combination with KEYTRUDA® (pembrolizumab) in solid tumours, a Phase I study of MRx0518 in a neoadjuvant setting for patients with solid tumours, a Phase I study of MRx0518 in patients with pancreatic cancer and a Phase I/II study of MRx-4DP0004 in asthma. Preclinical-stage programmes include candidates for CNS disease such as Parkinson's disease and other neurodegenerative conditions. The Company has a research collaboration with MSD, a tradename of Merck & Co., Inc., Kenilworth, NJ, USA, to discover and develop Live Biotherapeutics for vaccines.
For more information, refer to https://www.4dpharmaplc.com.
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