Join us

At 4D pharma, we understand that developing a new therapeutic class is challenging. We also understand that our people are our greatest resource – and we look to recruit ambitious and talented individuals from all over the world to be part of this exciting new area of medicine.

Please see our current career opportunities below:

Purpose of the Job

The successful candidate will provide technical support to the activities of the Microbiology (Isolation) Group in 4D Pharma Research Ltd. The candidate will be responsible for supporting the team in performing characterisation of bacteria, as well as preparing cultures for screening assays and preclinical studies. Previous practical experience in Microbiology and excellent aseptic technique are essential. Full training will be provided.

Experience / Qualifications Required

  • This position has a minimum requirement of a HND in microbiology, biochemistry, biology, or biomedical sciences or relevant experience
  • Competency in a variety of microbiological laboratory techniques
  • Experience with bacterial culturing techniques, including strict anaerobes would be advantageous
  • Ability to follow SOPs and an accurate way of working in the laboratory
  • Excellent organisational skills and accurate record keeping, attention to detail

Key Areas of Responsibility

  • Provide technical support to the 4D Pharma Isolation team
  • Perform microbiological laboratory techniques and protocols
  • Keep accurate and detailed records of data
  • Attend and contribute to research group meetings
  • Out of hours work when require

How to Apply

Please send all applications including a CV and covering letter to hr@4dpharmaplc.com.

Purpose of the Job

The successful candidate will primarily provide scientific expertise to the activities of the Discovery II Host team at 4D Pharma Research Ltd in Aberdeen. The primary focus of the team is to investigate the mechanisms behind the host-microbe interactions of our preclinical LBP candidates. Proficiency in running a variety of cellular and molecular techniques is required along with independent and flexible working. The post-holder will also be responsible for writing reports and SOPs, contributing to writing papers, present at internal and external meetings.

Experience / Qualifications Required

  • PhD Degree or Higher National Certificate in molecular biology, biomedical sciences, or other science-related discipline or at least 5 years experience working in an industrial environment in a similar role
  • Proven expertise in immunology
  • Competency in designing and developing cell-based assays to investigate the MoA of LBP candidates
  • Competency with isolation and culture of primary cells from tissue samples (e.g. gut, spleen, lymph nodes) or human samples (e.g. blood)
  • Proven expertise in single-cell analysis techniques (e.g. multiparameter flow cytometry)
  • Data analysis and interpretation
  • Keep accurate and detailed records of produced results
  • Good organisational and communication skills
  • Ability to work both within a team and independently
  • Experience with basic microbiology techniques is desirable

Key Areas of Responsibility

  • Run assay development and validation for the characterisation of LBPs
  • Analyse data and report results to the Team Leader and senior members of the team
  • Perform laboratory techniques and protocols according to SOPs
  • Provide scientific support to the Discovery II (Host) team
  • Keep accurate and detailed records of data
  • Attend and contribute to research group meetings
  • Train junior members of the team
  • Represent the company at international conferences

How to Apply

Please send all applications including a CV and covering letter to hr@4dpharmaplc.com.

Purpose of the Job

The successful candidate will perform testing required to support the core research and development program of the Discovery I Micro team at 4D Pharma Research in Aberdeen. The primary focus of the Discovery 1 Micro team is to carry out high-throughput and secondary screening of 4D Pharma’s strain library to identify candidate LBPs capable of modulating host-microbe interactions. The Senior Microbiologist is required to make scientific observations, maintain detailed workbooks/documentation and ensure all documentation fulfils generally accepted professional/industry standards. The senior scientist will be expected to propose new screening strategies and introduce and validate new screening approaches/methods ensuring they are current and compliant with industry standards and regulations. Requirements also include maintaining a thorough understanding of 4D Pharma’s services, technical principles and applications. Proficiency in running a variety of assays and molecular techniques are required along with independent and flexible working. The post holder will also be responsible for writing reports and SOPs, contributing to writing papers and present findings at internal and external meetings.

Essential Qualifications:

  • PhD Degree in Microbiology with expertise in human gut biology or immunology.
  • At least 5 years of post doc experience or 5 years’ experience working in an industrial en­vironment in a similar role.

Essential experience:

  • Competency with microbiology techniques especially in the cultivation of anaerobic microbes.
  • Competency with cell culture techniques.
  • Competency in a range of screening assays relevant to host-microbe interactions.
  • Expertise in running anaerobic bioreactors and in the techniques used to monitor microbial community composition.
  • Experience with biofilm-related techniques- total biomass, viability and susceptibility testing.
  • Experience in immunological assays.

Desirable experience:

  • Experience in assays using co-culture systems (bacteria & host cells).
  • HPLC detection and quantification of small molecules/secondary metabolites of interest in cell-free supernatants or extracts.
  • Competency in a variety of molecular laboratory techniques, including nucleic acid extraction, PCR and qPCR and imaging techniques such as CLSM and SEM.
  • Bioinformatics- genome mining.

Personal skills:

  • Contribute ideas and suggestions to improve standard laboratory techniques, improve protocols, processes and equipment.
  • Demonstrate a consistently high level of quality of work.
  • Create/revise SOPs, laboratory records and other related documentation as assigned.
  • Good organisational and communication skills.
  • Good problem solving skills- ability to “think out of the box”.
  • Introduce and validate new screening approaches/methods that are current and compliant with industry standards and regulations.
  • Experience of training other team members in relevant microbiological techniques.
  • Team worker.

Key Areas of Responsibility

  • Running assay development and validation for the discovery and characterisation of LBPs, in particular where gut cells and bacteria are involved.
  • Introduce and validate new screening approaches/methods ensuring they are current and compliant with industry standards and regulations.
  • Report results to the Team Leader and senior members of the team.
  • Perform laboratory techniques and protocols according to SOPs and provide technical support to the Discovery I Micro team.
  • Interact and liase with the Discovery I Host team.
  • Keep accurate and detailed records of data.
  • Attend and contribute to research group meetings and external event.

How to Apply

Please send all applications including a CV and covering letter to hr@4dpharmaplc.com.

Purpose of the Job

The successful candidate will perform testing required to support the core research and development program of the Discovery I Micro team at 4D Pharma Research in Aberdeen. The primary focus of the Discovery 1 Micro team is to carry out high-throughput and secondary screening of 4D Pharma’s strain library to identify candidate LBPs capable of modulating host-microbe interactions. The Research Scientist is required to make scientific observations, maintain detailed workbooks/ documentation and ensure all documentation fulfils generally accepted professional/industry standards. The Research scientist will be expected to propose new screening strategies and introduce and validate new screening approaches/methods ensuring they are current and compliant with industry standards and regulations. Requirements also include maintaining a thorough understanding of 4D Pharma’s services, technical principles and applications. Proficiency in running a variety of assays and molecular techniques are required along with independent and flexible working. The post holder will also be responsible for writing reports and SOPs, contributing to writing papers and present findings at internal and external meetings.

Essential Qualifications

  • PhD Degree in Microbiology, Biomedical sciences or other closely-related discipline or at least 5 years of experience working in an industrial environment in a similar role.

Essential experience

  • Competency with microbiology techniques especially in the cultivation of anaerobic microbes.
  • Competency with cell culture techniques.
  • Competency in a range of screening assays relevant to host-microbe interactions.
  • Expertise in HPLC- extraction, detection and quantification of small molecules/secondary metabolites of interest in cell-free supernatants or extracts.

Desirable experience

  • Experience in assays using co-culture systems (bacteria & host cells)
  • Competency in a variety of molecular laboratory techniques, including nucleic acid extraction, PCR and qPCR and imaging techniques such as CLSM and SEM.
  • Expertise in running anaerobic bioreactors and in the techniques used to monitor microbial community composition.
  • Experience with biofilm-related techniques- total biomass, viability and susceptibility testing.
  • Experience in immunological assays.
  • Bioinformatics- genome mining and NGS.

Personal skills

  • Contribute ideas and suggestions to improve standard laboratory techniques, improve protocols, processes and equipment.
  • Introduce and validate new screening approaches/methods that are current and compliant with industry standards and regulations.
  • Create/revise SOPs, laboratory records and other related documentation as assigned.
  • Good organisational and communication skills.
  • Good problem solving skills- ability to “think out of the box”.
  • Team worker.

Key Areas of Responsibility

  • Running assay development and validation for the discovery and characterisation of LBPs, in particular where gut cells and bacteria are involved.
  • Introduce and validate new screening approaches/methods ensuring they are current and compliant with industry standards and regulations.
  • Report results to the Team Leader and senior members of the team.
  • Perform laboratory techniques and protocols according to SOPs and provide technical support to the Discovery I Micro team.
  • Interact and liase with the Discovery I Host team.
  • Keep accurate and detailed records of data.
  • Attend and contribute to research group meetings and external event.

How to Apply

Please send all applications including a CV and covering letter to hr@4dpharmaplc.com.

Purpose of the Job

The successful candidate will provide technical support on the fermentation process of anaerobic bacteria using a bench-top fermenter with the development team in 4D Pharma Research Ltd. The primary focus of the group is to optimise bioprocesses of the strains which will go into industrial production. The candidate will also provide technical support to evaluate purity, potency and stability of the bacteria. The candidate will be responsible for the preparation and execution of various experiments and should therefore have a strong background in the culturing, enumeration and aseptic handling of microorganisms.

Previous experience in a microbiology laboratory is essential to this position as is the ability to work independently and with attention to detail. Candidates who have previously worked with anaerobic bacteria are particularly desirable.

Experience / Qualifications Required

  • This position has a minimum requirement of a Bachelor’s Degree in biotechnology or microbiology.
  • Industry-relevant experience with microbial product development for minimum of 1 year.
  • Experience with bench bioreactors.
  • Experience with bacterial culturing, enumeration techniques and purity evaluation.
  • Experience with aseptic techniques.
  • Experience with anaerobic bacteria would be advantageous.
  • Familiarity with quality assurance documentation.

Key Areas of Responsibility

  • Provide technical support for experiment preparation and decontamination.
  • Provide technical support for fermentation process and analysis.
  • Provide technical support for enumeration techniques and purity evaluation.
  • Generation of bacterial cell banks.
  • Keep accurate and detailed records of data and reporting up to date.
  • Involvement in planning-weekly work schedule.
  • General laboratory maintenance.

Personal skills

  • Good organisational and communication skills.
  • Independent and proactive.
  • Flexible with working hours.

How to apply

Please send all applications to: hr@4dpharmaplc.com including your CV and covering letter.

We always welcome applications from talented individuals even if a role is not advertised we would be keen to hear from you. Please send your CV to hr@4dpharmaplc.com

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