Join us

At 4D pharma, we understand that developing a new therapeutic class is challenging. We also understand that our people are our greatest resource – and we look to recruit ambitious and talented individuals from all over the world to be part of this exciting new area of medicine.

Please see our current career opportunities below:

About the Company

4D pharma Cork Ltd is a campus company in Cork whose aim is to investigate how variations in the composition of bacterial communities in the gut can be used for the diagnosis and treatment of disease. Recent advances in the field have highlighted the importance of the gut microbiome, not only for the development of safe and efficacious new therapeutics, but also for the discovery of novel personalised diagnostic tools.

4D pharma Cork Ltd is a subsidiary of 4D pharma plc (http://www.4dpharmaplc.com/), a UK pharmaceutical company developing Live Biotherapeutics, a novel and emerging class of drugs. 4D pharma Cork is developing a diagnostic platform, MicroDx, across multiple disease areas, mirroring 4D’s proprietary MicroRx platform for the discovery of live biotherapeutics.


Purpose of the Job

We are seeking a highly motivated and experienced bioinformatician/biostatician/computational biologist to join the 4D pharma Cork bioinformatics team to work on exciting EU Horizon 2020 funded project. The project is focused on microbiome applications for sustainable food systems and consists of a consortium of 34 partners from Europe, Canada and New Zealand. This is a four year position which may be extended by the company after the project. The successful candidate will analyse and integrate microbiome, clinical, dietary and metabolomics datasets to identify interactions between the microbiome, health and disease to inform innovative sustainable food products to promote health. The individual must be capable of working independently as well as part of a team to achieve the deliverables of the project.

The successful candidate must be available to start immediately.


Experience / Qualifications Required

  • At a minimum, a PhD in one of the following areas: bioinformatics/biostatistics/computational biology/machine learning
  • Significant experience in the analysis of high-throughput datasets and integrative analysis of diverse omics datasets from different platforms.
  • Track record of independent critical thinking and scientific achievement evidenced by excellent publication record.
  • Experience with two or more computational/statistical languages such as but not limited to R/bioconductor, Java, Perl, python, stata and Bash shell-scripting experience (Unix).
  • The candidate should be knowledgeable, highly motivated, creative, and collaborative.
  • Excellent verbal and written communication skills
  • Excellent interpersonal and communication skills and an attention to detail.
  • Ability to work independently or as part of a team.
  • A committment to maintain and develop personal and management skills by undertaking mandatory and other training as required.
  • Garda vetting and international police clearance check may form part of the selection process.


Key Areas of Responsibility

  • Carry out biostatistical and integrative analysis of different datasets e.g. microbiome, metabolomic, dietary and clinical metadata to meet the project objectives.
  • Prepare progress reports and presentations on company research activities and present data at project meetings as required.
  • Liaise with project team, to ensure timely processing of data to advance the research programme.
  • Maintain and manage all data in a safe and secure manner at all times.
  • Engage in appropriate training and professional development opportunities to develop research skills and competencies as required by the Directors and Site Manager.
  • Participate in training as required to develop or augment core skill-sets.
  • Promote and maintain a positive teamwork environment.


How to apply

Please send all applications to: corkrecruitment@4dpharmaplc.com. Candidates should submit a curriculum vitae including contact details for 2 referees along with a covering letter. For any queries or further information on the post please contact Prof Paul O’ Toole (pwotoole@ucc.ie) or Dr Ian Jeffery (i.jeffery@4dpharmaplc.com).

About the Company

4D Pharma PLC is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drugs that contain live organisms for the prevention, treatment or cure of disease. 4D Pharma is a world leader in the LBP field and currently has two clinical stage programmes (in IBS and IBD) and a strong pipeline of pre-clinical programmes in autoimmunity, inflammation, oncology and CNS disease.


Purpose of the Job

Applications are invited for the role of Scientist/Senior Scientist to join the research team at 4D Pharma Research Ltd in Aberdeen (UK). The successful candidate will provide scientific expertise in assay development for drug discovery for the proprietary MicroRx platform, identifying candidate LPBs for different therapeutic areas. This is mainly focussed on defining suitable properties of LBPs in novel disease areas using appropriate in vitro and ex vivo readouts. The role will require proven expertise in a range of cell biological and immunological techniques, and the proven ability to translate these skills into robust and reliable data. The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property.


Experience / Qualifications Required

  • A PhD with relevant post-doctoral or industry experience (>3-4 years) in drug discovery, cell biology, immunology or a related discipline
  • Solid experience in a range of in vitro and ex vivo immunology techniques and proven expertise in cell-based and biochemical assay development (primary cell culture, co-culture systems, multiparameter flow cytrometry, multiplex assays, confocal microscopy and signalling pathway analysis)
  • Ideally a Home Office personal/project licence holder (or equivalent)
  • Thorough understanding of the gut microbiome and host-microbe interactions
  • Highly motivated and innovative with the ability to work independently and integrate into a multidisciplinary team of microbiologists and molecular biologists
  • Good organisational and communication skills proven by previous line management and supervision experience

How to apply

Please send all applications to:

Lucy Christie
Life Sciences Innovation Building
Cornhill Road
Aberdeen
AB25 2ZS
Email hr@4dpharmaplc.com
Telephone 01224 900 460

We always welcome applications from talented individuals even if a role is not advertised we would be keen to hear from you. Please send your CV to hr@4dpharmaplc.com

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