Join us

At 4D pharma, we understand that developing a new therapeutic class is challenging. We also understand that our people are our greatest resource – and we look to recruit ambitious and talented individuals from all over the world to be part of this exciting new area of medicine.

Please see our current career opportunities below:


About the Company

4D pharma plc is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drugs that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programmes (in IBS, IBD, oncology and asthma) and a strong pipeline of additional pre-clinical programmes in autoimmunity, inflammation, and CNS disease.


Purpose of the Job

Applications are invited for the role of Senior Scientist to join the research team at 4D Pharma Research Ltd in Aberdeen (UK), the research division of 4D pharma.

The successful candidate will provide scientific expertise in assay development for drug discovery for 4D's proprietary MicroRx platform, identifying candidate LPBs for different therapeutic areas. This is mainly focussed on defining suitable properties of LBPs in novel disease areas using appropriate in vitro and ex vivo readouts by integrating cellular, molecular, and immune endpoints to study the modulation of the host immune system and support translational development of LBPs.

The role will require proven hands-on, lab-based expertise in a range of cell biological and immunological techniques, and the proven ability to translate these skills into robust and reliable data.

The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property. The post holder will be expected to personally execute laboratory activities as required operationally, and to supervise and mentor junior team members in various lab-based activities. Weekend or out-of-hours work will be required periodically, based on operational requirements.


Experience / Qualifications Required

  • PhD in immunology, oncology, or other relevant discipline, ideally with 3 years’ experience working in an industrial environment in a similar role
  • Strong knowledge background and research training in immunology and/or cellular biology as evidenced by a strong publication record
  • Hands-on experience in a variety of laboratory techniques, including, cell culture, flow cytometry and immunological phenotyping
  • Experience working with in vivo work, Personal licence ownership or willingness to acquire licence desirable
  • Planning, designing, executing, and analysing pre-clinical in vitro and ex-vivo studies in the immunological field
  • Excellent analytical, problem-solving, and organisational skills with attention to detail
  • Strong communication and interpersonal skills
  • Experience in supervising junior members of staff


Key Areas of Responsibility

  • Assay development and validation for the characterisation of LBPs
  • Analyse data and report results to the Team Leader and senior members of the team
  • Perform laboratory techniques and protocols according to SOPs
  • Contribute to write SOPs where necessary
  • Provide scientific support to the Discovery (Host) team
  • Keep accurate and detailed records of data
  • Attend and contribute to research group meetings
  • Train junior members of the team


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D pharma plc is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drugs that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programmes in oncology, asthma, IBS and IBD, and a strong pipeline of additional pre-clinical programmes in CNS disease, oncology autoimmunity and inflammation.


Purpose of the Job

Applications are invited for the role of Research Scientist - Microbiologist, to join the research team at 4D Pharma Research Ltd in Aberdeen (UK), the research division of 4D pharma. This position will require the provision of scientific expertise to 4D's proprietary MicroRx platform, for the early discovery of new LBPs in novel therapeutic areas. This successful candidate will investigate the mechanisms through which bacterial candidates confer disease protection on the host. This role will involve mining the 4D pharma bacterial culture collection to identify and characterise microbial metabolites with the potential to mediate host-microbe interactions.

This work will include the characterisation of the metabolic profiles of bacterial strains both at an individual and community level using targeted and untargeted metabolomic analysis tools. Previous experience in the analysis of faecal-microbiota metabolic signatures and short chain fatty acid quantification would be of advantage to this role. A strong background in a wide range of microbiological techniques is required for this position with a particular emphasis on mass spectrometry, HPLC and techniques required for the quantification of bacteria metabolites. Knowledge of host-microbe communication, ideally in the field of gut microbiome research, is also highly desirable.

We are seeking an individual with a proven ability to develop and undertake high quality research. The post holder will be expected to engage with the wider research activities of the group, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property.


Required Experience / Qualifications:

  • PhD with relevant post-doctoral or industry experience (>5 years) in Microbiology, Biochemistry, Biotechnology or a related discipline.
  • Expertise in the detection, quantification, and purification of bacterial metabolites.
  • Experience in the in silico analysis of bacterial metabolic pathways.
  • Experience in a range of microbiological techniques and proven expertise in assay development.
  • Excellent organisational and project management experience.
  • Excellent verbal and written communication skills.


Desirable skills and abilities:

  • Thorough understanding of the gut microbiome and host-microbe interactions.
  • Demonstrable expertise in the design and execution of screening assays relevant to host-microbe interactions.
  • Ability to apply relevant models and techniques and experience developing new ones.
  • Highly motivated and innovative with the ability to work independently and integrate into a multidisciplinary team of microbiologists and molecular biologists.
  • Assess resource requirements and deploy them effectively.
  • Prioritise workload effectively in response to deadlines.
  • Previous line management/supervisory experience.


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D pharma plc is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drug that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programmes in oncology, asthma, IBS and IBD, and a strong pipeline of additional pre-clinical programmes in CNS disease, oncology autoimmunity and inflammation.


Purpose of the Job

Applications are invited for the role of Research Scientist – Immunology, to join the research team at 4D Pharma Research Ltd in Aberdeen (UK), the research division of 4D pharma plc. The successful candidate will provide scientific expertise in assay development for drug discovery for 4D's proprietary MicroRx platform, identifying candidate LPBs for different therapeutic areas. This is mainly focussed on defining suitable properties of LBPs in novel disease areas using appropriate in vitro and ex vivo readouts by integrating cellular, molecular, and immune endpoints to study the modulation of the host immune system and support translational development of LBPs.

The role will require proven current hands-on, lab-based expertise in a range of immunological techniques, proficiency in multi-colour flow cytometry, and a proven ability to translate these skills into robust and reliable data. The post holder will be expected to personally execute laboratory activities as required operationally, and to supervise and mentor junior team members in various lab-based activities. Weekend or out-of-hours work will be required periodically, based on operational requirements. A team-oriented approach to work is required. The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property.


Experience / Qualifications Required

  • PhD in immunology, or other relevant discipline, ideally with 3 years’ experience working in an industrial environment in a similar role
  • Strong knowledge background and research training in immunology
  • Hands-on experience in a variety of laboratory techniques: multi-colour flow cytometry, cell culture and immunophenotyping are essential
  • Experience working with in vivo work: Experience of immunological in vivo work essential; Personal licence ownership or willingness to acquire licence desirable
  • Planning, designing, executing, and analysing pre-clinical in vitro and ex vivo studies in the immunological field
  • Excellent analytical, problem-solving, and organisational skills with attention to detail
  • Strong communication and interpersonal skills
  • Experience in supervising junior members of staff


Key Areas of Responsibility

  • Assay development and validation for the characterisation of LBPs
  • Analyse data and report results to the Team Leader and other senior members of staff
  • Perform laboratory techniques and protocols according to SOPs
  • Contribute to writing SOPs where necessary
  • Provide scientific support to the Discovery (Host) team
  • Keep accurate and detailed records of data
  • Attend and contribute to research group meetings
  • Train junior members of the team


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

We always welcome applications from talented individuals even if a role is not advertised we would be keen to hear from you. Please send your CV to hr@4dpharmaplc.com

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