Join us

At 4D pharma, we understand that developing a new therapeutic class is challenging. We also understand that our people are our greatest resource – and we look to recruit ambitious and talented individuals from all over the world to be part of this exciting new area of medicine.

Please see our current career opportunities below:


About the Company

4D Pharma PLC is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) represent a new class of drugs that contain live bacterial strains for the prevention, treatment, or cure of disease. 4D Pharma is a world leader in the LBP field and currently has a number of clinical stage programmes (in oncology, asthma, IBS and IBD) and a strong pipeline of pre-clinical programmes in autoimmunity, inflammation, oncology and CNS disease.


Purpose of the Job

Applications are invited for the role of Senior Scientist to join the research team at 4D Pharma Research Ltd in Aberdeen (UK).

The successful candidate will provide scientific expertise in assay development for drug discovery for the proprietary MicroRx platform, identifying candidate LPBs for different therapeutic areas. This is mainly focussed on defining suitable properties of LBPs in novel disease areas using appropriate in vitro and ex vivo readouts by integrating cellular, molecular, and immune endpoints to study the modulation of the host immune system and support translational development of LBPs.

The role will require proven hands-on, lab-based expertise in a range of cell biological and immunological techniques, and the proven ability to translate these skills into robust and reliable data.

The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property. The post holder will be expected to personally execute laboratory activities as required operationally, and to supervise and mentor junior team members in various lab-based activities. Weekend or out-of-hours work will be required periodically, based on operational requirements.


Experience / Qualifications Required

  • PhD in immunology, oncology, or other relevant discipline, ideally with 3 years’ experience working in an industrial environment in a similar role
  • Strong knowledge background and research training in immunology and/or cellular biology as evidenced by a strong publication record
  • Hands-on experience in a variety of laboratory techniques, including, cell culture, flow cytometry and immunological phenotyping
  • Experience working with in vivo work, Personal licence ownership or willingness to acquire licence desirable
  • Planning, designing, executing, and analysing pre-clinical in vitro and ex-vivo studies in the immunological field
  • Excellent analytical, problem-solving, and organisational skills with attention to detail
  • Strong communication and interpersonal skills
  • Experience in supervising junior members of staff


Key Areas of Responsibility

  • Assay development and validation for the characterisation of LBPs
  • Analyse data and report results to the Team Leader and senior members of the team
  • Perform laboratory techniques and protocols according to SOPs
  • Contribute to write SOPs where necessary
  • Provide scientific support to the Discovery (Host) team
  • Keep accurate and detailed records of data
  • Attend and contribute to research group meetings
  • Train junior members of the team


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D Pharma PLC is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drugs that contain live organisms for the prevention, treatment or cure of disease. 4D Pharma is a world leader in the LBP field and currently has two clinical stage programmes (in IBS and IBD) and a strong pipeline of pre-clinical programmes in autoimmunity, inflammation, oncology and CNS disease.


Purpose of the Job

The successful candidate will primarily provide technical, laboratory-based assistance to the activities of the Discovery Host team at 4D Pharma Research Ltd in Aberdeen.

The primary focus of the team is to perform high-throughput screening assays investigating host-microbe interactions for the identification of new LBPs in different therapeutic areas.

Proficiency in running a variety of cellular and molecular techniques are required along with independent and flexible working. The post holder will also be responsible for writing reports and SOPs, contributing to writing papers, present at internal and external meetings. Weekend or out-of-hours work will be required periodically, based on operational requirements.

This is a 9 month maternity cover vacancy.


Experience / Qualifications Required

  • MSc or PhD in molecular biology, biomedical sciences, or related discipline or at least 5 years’ experience
  • Proven expertise in gut biology and/or mucosal immunology
  • Competency in assay development
  • Competency with cell culture techniques
  • Competency with isolation and culture of primary cells from tissue (e.g. gut) or blood
  • Competency in a variety of molecular laboratory techniques, including qPCR or flow cytometry or imaging techniques
  • Keep accurate and detailed records of produced results
  • Good organisational and communication skills
  • Able to work both as part of a Team and independently
  • Desirable: Experience with basic microbiology techniques


Key Areas of Responsibility

  • Running assay development and validation for the discovery and characterisation of LBPs, in particular where gut cells and bacteria are involved
  • Report results to the Team Leader and senior members of the team
  • Perform laboratory techniques and protocols according to SOPs
  • Contribute to write SOPs where necessary
  • Contribute to expand the assay capability of the proprietary 4D Pharma MRx platform
  • Provide scientific support to the Discovery Host team
  • Keep accurate and detailed records of data
  • Attend and contribute to research group meetings
  • Training of junior members of the team
  • Represent the company to international conferences
  • Able to work both independently and as a part of a team


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D Pharma plc is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drugs that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has numerous clinical stage programmes in Oncology, Respiratory and Gastrointestinal diseases, as well as a strong pipeline of pre-clinical programmes in CNS, and autoimmune/inflammatory disease.

The Company is based in Leeds (UK) and is listed on AIM (reporting under IFRS) and is expecting to dual list on Nasdaq Q1 2021 (reporting under USGAAP).


Purpose of the Job

We have an excellent opportunity for a qualified accountant or part qualified accountant looking to take a first-hand role in helping to develop the finance function, reporting analysis, budgets, statutory reporting, VAT and Payroll, along with other project work.

Reporting directly to the Group Finance Director you will be required to utilise excellent communication skills to liaise with all departments, suppliers, and senior management to ensure effective financial management and reporting across a group of companies in Great Britain, Europe and the USA.

The position will be based in the head office in Leeds, UK, with remote working.


Experience / Qualifications Required

  • Qualified / Part Qualified CA, ACCA or CIMA
  • Excellent Excel, IT and data management skills with a good understanding of lookups, sumifs, pivot tables and other functions
  • Effective communication skills
  • Strong organisations skills and an attention to detail
  • Commercially aware
  • Self motivated


Desirable Skills & Experience

  • The ability to put together a set of management accounts, budgets, forecasts, statutory accounts or other reports
  • Microsoft business central on premise (Navision) experience (other ERP experience useful) – the company currently uses Xero and are looking to migrate during 2021
  • Practice knowledge / experience of reporting under both USGAAP and IFRS
  • Understanding of VAT / TVA / IVA and other European and international tax regimes
  • Understanding of Group consolidations
  • Audit training
  • Spanish language skills


Key Areas of Responsibility

Working as part of a small team you will have exposure to most aspects of the finance function. The role will focus on reporting and compliance as the group moves towards meeting Nasdaq listing requirements. This will require a flexible approach in an expanding department as you assist with both reporting and the development of revised controls, budgetary information and reporting structures while phasing out the use of third-party advisors.

As part of the team, you will be expected to be involved with the purchase ledger and authorisation process, bank payments, ledger management, VAT and other taxes, so a keen eye for detail and technical knowledge of numerous areas would be used and/or developed.


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D pharma plc is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drugs that contain live organisms for the prevention, treatment, or cure of disease. 4D pharma is a world leader in the LBP field and has completed trials in IBS and IBD, current trials are being conducted in oncology, COVID-19 and asthma and we have a strong pre-clinical pipeline with programs in CNS and autoimmune/inflammatory disease.


Purpose of the Job

To support 4D's expanding clinical pipeline, we are looking for new Clinical Study Managers who will be predominately office based in our headquarters in Leeds. These individuals will report to their respective Therapeutic Programme Development Director and may also have line management responsibility for Clinical Trial Assistant(s).

A large part of the role will involve managing CROs we work with to take 4D pharma’s pipeline into and through the clinic on an international basis.

This position would suit an individual with both CRO and Pharmaceutical experience who would like to be part of a team at the cutting edge of microbiome research.


Key Areas of Responsibility

  • Oversee CROs and other external vendors to ensure completion of trials within timelines and budget and to the required quality
  • Develop productive working relationships with internal colleagues to ensure high quality and timely delivery of trials
  • Develop productive and supportive relationships with Investigational Sites (as appropriate)
  • Define and manage project risks, establishing key risks and mitigating those from the point of protocol development through to study archive
  • Ensure that Project Plans for assigned Trials are accurate and up to date
  • Ensure that budgets for assigned Trials are established and maintained throughout
  • Oversight of IMP management
  • Contribute to the design of trials from an operational delivery perspective
  • Organise and participate in Investigator Meetings, presenting trial data and training to clinical staff
  • Participate in the evaluation and selection of Clinical Research Organisations (CROs) and required external vendors
  • Co-ordinate the establishment and execution of trial contracts
  • Ensure clinical trials are run in accordance with SOPs and relevant regulatory guidelines
  • Ensure issues are reviewed with the Quality Team and reported within the QMS accordingly
  • Oversee TMF activities to ensure they are accurate and complete
  • Provide regular study status reports to the Drug Development Lead and Senior Management
  • Contribute to process improvement initiatives
  • Participate in the development and review of 4D pharma SOPs and policies
  • Provide line management for Clinical Trial Assistant(s)


Essential Experience

  • Consistent track record in successfully running multi-site patient clinical trials from study design to archiving
  • CRO oversight and managing outsourced clinical trials
  • Managing and controlling study budgets
  • Detailed knowledge of ICH/GCP and regulatory guidelines
  • Significant understanding of core teams within the Clinical Trial setting; Regulatory, Safety, Medical Writing, Data Management, Statistics, Laboratories, and IMP management
  • Ability to work effectively and independently to fast-moving timelines within a fast-paced working environment
  • A flexible and collaborative nature
  • Operationally strong and delivery focused
  • Ability to travel as required within the UK and outside (current full driving licence and valid passport)
  • Fluent in written and spoken English


Desirable Experience

  • Line management
  • Oncology or Neurodegeneration experience
  • Conducting adaptive design studies
  • Conducting studies with a risk-based monitoring approach
  • Experience with Electronic Clinical Outcome Assessment (eCOA)


Qualifications Required

  • Degree in a health or scientific discipline or relevant industry experience of 10 years or more
  • A minimum of 3 years Clinical Trial Management experience


How to apply

Please send all applications to;

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

We always welcome applications from talented individuals even if a role is not advertised we would be keen to hear from you. Please send your CV to hr@4dpharmaplc.com

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