Join us

At 4D pharma, we understand that developing a new therapeutic class is challenging. We also understand that our people are our greatest resource – and we look to recruit ambitious and talented individuals from all over the world to be part of this exciting new area of medicine.

Please see our current career opportunities below:


About the Company

4D pharma plc is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drugs that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programmes (in IBS, IBD, oncology and asthma) and a strong pipeline of additional pre-clinical programmes in autoimmunity, inflammation, and CNS disease.


Purpose of the Job

Applications are invited for the role of Senior Scientist to join the research team at 4D Pharma Research Ltd in Aberdeen (UK), the research division of 4D pharma.

The successful candidate will provide scientific expertise in assay development for drug discovery for 4D's proprietary MicroRx platform, identifying candidate LPBs for different therapeutic areas. This is mainly focussed on defining suitable properties of LBPs in novel disease areas using appropriate in vitro and ex vivo readouts by integrating cellular, molecular, and immune endpoints to study the modulation of the host immune system and support translational development of LBPs.

The role will require proven hands-on, lab-based expertise in a range of cell biological and immunological techniques, and the proven ability to translate these skills into robust and reliable data.

The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property. The post holder will be expected to personally execute laboratory activities as required operationally, and to supervise and mentor junior team members in various lab-based activities. Weekend or out-of-hours work will be required periodically, based on operational requirements.


Experience / Qualifications Required

  • PhD in immunology, oncology, or other relevant discipline, ideally with 3 years’ experience working in an industrial environment in a similar role
  • Strong knowledge background and research training in immunology and/or cellular biology as evidenced by a strong publication record
  • Hands-on experience in a variety of laboratory techniques, including, cell culture, flow cytometry and immunological phenotyping
  • Experience working with in vivo work, Personal licence ownership or willingness to acquire licence desirable
  • Planning, designing, executing, and analysing pre-clinical in vitro and ex-vivo studies in the immunological field
  • Excellent analytical, problem-solving, and organisational skills with attention to detail
  • Strong communication and interpersonal skills
  • Experience in supervising junior members of staff


Key Areas of Responsibility

  • Assay development and validation for the characterisation of LBPs
  • Analyse data and report results to the Team Leader and senior members of the team
  • Perform laboratory techniques and protocols according to SOPs
  • Contribute to write SOPs where necessary
  • Provide scientific support to the Discovery (Host) team
  • Keep accurate and detailed records of data
  • Attend and contribute to research group meetings
  • Train junior members of the team


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D pharma plc is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drugs that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programmes in oncology, asthma, IBS and IBD, and a strong pipeline of additional pre-clinical programmes in CNS disease, oncology autoimmunity and inflammation.


Purpose of the Job

Applications are invited for the role of Research Scientist - Microbiologist, to join the research team at 4D Pharma Research Ltd in Aberdeen (UK), the research division of 4D pharma. This position will require the provision of scientific expertise to 4D's proprietary MicroRx platform, for the early discovery of new LBPs in novel therapeutic areas. This successful candidate will investigate the mechanisms through which bacterial candidates confer disease protection on the host. This role will involve mining the 4D pharma bacterial culture collection to identify and characterise microbial metabolites with the potential to mediate host-microbe interactions.

This work will include the characterisation of the metabolic profiles of bacterial strains both at an individual and community level using targeted and untargeted metabolomic analysis tools. Previous experience in the analysis of faecal-microbiota metabolic signatures and short chain fatty acid quantification would be of advantage to this role. A strong background in a wide range of microbiological techniques is required for this position with a particular emphasis on mass spectrometry, HPLC and techniques required for the quantification of bacteria metabolites. Knowledge of host-microbe communication, ideally in the field of gut microbiome research, is also highly desirable.

We are seeking an individual with a proven ability to develop and undertake high quality research. The post holder will be expected to engage with the wider research activities of the group, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property.


Required Experience / Qualifications:

  • PhD with relevant post-doctoral or industry experience (>5 years) in Microbiology, Biochemistry, Biotechnology or a related discipline.
  • Expertise in the detection, quantification, and purification of bacterial metabolites.
  • Experience in the in silico analysis of bacterial metabolic pathways.
  • Experience in a range of microbiological techniques and proven expertise in assay development.
  • Excellent organisational and project management experience.
  • Excellent verbal and written communication skills.


Desirable skills and abilities:

  • Thorough understanding of the gut microbiome and host-microbe interactions.
  • Demonstrable expertise in the design and execution of screening assays relevant to host-microbe interactions.
  • Ability to apply relevant models and techniques and experience developing new ones.
  • Highly motivated and innovative with the ability to work independently and integrate into a multidisciplinary team of microbiologists and molecular biologists.
  • Assess resource requirements and deploy them effectively.
  • Prioritise workload effectively in response to deadlines.
  • Previous line management/supervisory experience.


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D pharma plc is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drug that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programmes in oncology, asthma, IBS and IBD, and a strong pipeline of additional pre-clinical programmes in CNS disease, oncology autoimmunity and inflammation.


Purpose of the Job

Applications are invited for the role of Research Scientist – Immunology – to join the research team at 4D Pharma Research Ltd in Aberdeen (UK). The successful candidate will provide scientific expertise in drug discovery for the proprietary MicroRx platform, identifying candidate LPBs for different therapeutic areas. This is mainly focussed on defining suitable properties of LBPs in novel disease areas using appropriate in vitro and ex vivo readouts by integrating cellular, molecular, and immune endpoints to study the modulation of the host immune system and support translational development of LBPs. The candidate will also be involved in pre-clinical efficacy studies and investigate the mechanisms behind LBP-host interactions. The role will require proven hands-on expertise in a range of immunological techniques, including human and murine cellular assays, immune cell isolation and differentiation (lymphoid and myeloid populations), ELISA-based assays, proficiency in multi-parameter flow cytometry, and a proven ability to translate these skills into robust and reliable data. The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property.


Experience / Qualifications Required

  • PhD in Immunology, or other relevant discipline, ideally with 3 years’ experience working in an industry environment in similar role
  • Proven expertise in innate immunology and/or microbe-host interactions
  • Strong experience in isolation, culturing and immunophenotyping of primary cells from blood or tissues
  • Experience in a variety of laboratory techniques such as multi-parameter flow cytometry (15+ colours), primary and immortalised cell culture, ELISA-based assays (multiplex), nucleic acid extraction (DNA and RNA), qPCR, immunofluorescence staining
  • Experience working in vivo essential; familiarity with animal models relevant to 4D pipeline (e.g., immuno-oncology, CNS, gastro-intestinal, asthma, autoimmune diseases). Personal licence ownership or willingness to acquire licence
  • Excellent analytical, problem-solving, and organisational skills with attention to detail
  • Strong communication and interpersonal skills and experience in supervising junior members of staff


Key Areas of Responsibility

  • Assay development and validation for the characterisation of LBPs
  • Analyse data and report results to the Team Leader and other senior members of staff
  • Perform laboratory techniques and protocols according to SOPs
  • Provide scientific support to the Discovery (Host) team
  • Keep accurate and detailed records of data
  • Attend and contribute to research group meetings
  • Train junior members of the team


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D pharma plc is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drug that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programmes in oncology, asthma, IBS and IBD, and a strong pipeline of additional pre-clinical programmes in CNS disease, oncology autoimmunity and inflammation.


Purpose of the Job

The successful candidate will provide technical support to the activities of the Microbiology Group at 4D Pharma Research Ltd in Aberdeen, the Research division of 4D pharma. The candidate will be responsible for supporting the team in performing microbial characterisation of bacterial strains, preparing bacterial cultures for screening assays and other ongoing projects. Previous practical experience in Microbiology and excellent aseptic technical skills are essential along with a degree of independent and flexible working. Training for specific assays and techniques will be provided. The post-holder will also be responsible for preparing reagents, maintaining stock levels and sample database management. The successful candidate will be flexible around start times as there will be early and late shifts required for the role.


Experience / Qualifications Required

  • BSc degree or Higher National Certificate (HND) in microbiology, biochemistry, biology or biomedical sciences
  • Competency in a variety of microbiological laboratory techniques.
  • Experience in bacterial culturing techniques is essential to this role and a knowledge of handling requirements for strict anaerobes would be highly valuable.
  • Strong aseptic technical skills.
  • Basic experience of molecular biology techniques would be advantageous.
  • Ability to follow SOPs and an accurate way of working in the laboratory.
  • Excellent organisational skills and accurate record keeping, attention to detail.


Key Areas of Responsibility

  • Provide technical support to the Microbiology team.
  • Perform microbiological laboratory techniques and protocols.
  • Keep accurate and detailed records of data.
  • Attend and contribute to research group meetings.
  • Flexible working hours with early and late shifts.


How to apply

Please send all applications to:

Lucy Christie

Group HR Manager

Email hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D pharma plc is a pharmaceutical company focussed on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drug that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programs in oncology, asthma, IBS and IBD, and a strong pipeline of additional pre-clinical programs in CNS disease, oncology autoimmunity and inflammation.


Purpose of the Job

Applications are invited for the role of Research Scientist in Neuroscience to join the research team at 4D Pharma Research Ltd in Aberdeen (UK). The successful candidate will provide scientific expertise in assay development for drug discovery using 4D pharma's proprietary MicroRx® platform to identify candidate LPBs for different therapeutic areas. This is mainly focussed on defining suitable properties of LBPs in CNS diseases using appropriate in vitro, in vivo and ex vivo readouts by integrating cellular, molecular, immune and neurological endpoints to study the modulation of the gut-brain axis and support translational development of LBPs. Knowledge of gut-microbiota-brain communication is highly desirable.

Technical requirements for this position include first-hand experience with techniques in cell and tissue culture, animal handling and behaviour, microscopy imaging as well as molecular biology techniques (e.g. transcriptomics), as well as the proven ability to translate these skills into robust and reliable data. The post holder will be expected to personally execute laboratory activities, and to supervise and mentor junior team members in various lab-based activities. We are seeking an individual with a proven ability to develop and undertake high quality research. The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property.


Experience / Qualifications Required

  • MSc. or Ph.D. in Neuroscience or other relevant discipline, ideally with a minimum of 3 years’ experience working in an industrial environment in a similar role
  • Strong background and research training in neuroscience, cellular and molecular biology, immunology, and/or microbiology
  • Experience in designing and performing routine and complex laboratory procedures and assays (in vitro and ex vivo), including molecular, cellular and biochemical techniques in order to understand the in-depth molecular signatures of cellular components of the gut-brain axis in health and disease
  • Interest in exploring mechanisms underlying protein misfolding/spread leading to neurodegeneration in the enteric, peripheral, and central nervous systems to uncover new therapeutic targets
  • Experience in conducting in vivo experiments to study disease pathophysiology from the gut to the brain and validate new targets
  • Personal licence ownership or willingness to acquire licence desirable
  • Expertise in data analysis focusing on one or more neurological disorder (i.e., Parkinson’s disease, Alzheimer’s disease, Stroke, etc.)
  • Proficiency with primary rodent and iPSC human neuronal cell cultures and complex in vitro models is preferred Interest and focus on interdisciplinary work, strong communication and interpersonal skills
  • Excellent analytical, problem-solving, and organisational skills with attention to detail
  • Experience in supervising junior members of staff


Key Areas of Responsibility

  • Assay development and validation for the characterisation of LBPs
  • Analyse data and report results to the Team Leader and other senior members of staff
  • Perform laboratory techniques and protocols according to SOPs
  • Provide scientific expertise to the Discovery (Host) team Keep accurate and detailed records of data
  • Attend and contribute to research group meetings
  • Train junior members of the team


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D Pharma PLC is a pharmaceutical company focused on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drugs that contain live organisms for the prevention, treatment or cure of disease. 4D Pharma is a world leader in the LBP field and currently has a number of clinical stage programs (in IBS, IBD, oncology and asthma) and a strong pipeline of additional pre-clinical programs in autoimmunity, inflammation, and CNS disease.

The Company is based in Leeds, UK, with subsidiaries in the UK, Europe and US. 4D pharma is dual listed on both AIM (DDDD) and Nasdaq (LBPS).


Purpose of the Job

We have an excellent opportunity for a Financial Analyst / Management Accountant looking to take a first-hand role in helping the finance function. Excellent modelling, budgeting, KPI analysis and variance reporting skills will be required though the role will also include numerous other accounting disciplines so broader experience is a must. Reporting directly to the Group Finance Director you will be required to utilize excellent communication skills to liaise with all departments, suppliers, and management to ensure effective financial management and reporting across a group of companies and departments.


Experience and Qualifications Required

  • A sound understanding of the interaction between statutory reporting requirements, group consolidations and various taxes, systems and controls
  • Ability to review, produce and/or assist with monthly management accounts and year end statutory accounts
  • Part Qualified and ideally working towards formal qualification of ACA/ACCA/CIMA
  • Advanced knowledge of Excel
  • A good working knowledge of other Microsoft applications with prior usage of Microsoft Business Central (formerly Navision) and experience in systems implementation being preferential but not required
  • Sound analytical skills, good planning and organization skills
  • Ability to communicate key financial information to non-finance personnel in a clear and concise way
  • Ability to build strong professional relationships with colleagues across differing functions
  • Understanding of data and execution of implementation plans
  • Strong attention to detail
  • Self-starter with the ability to identify problems, find solutions and to work independently


Key Areas of Responsibility

Working as part of a small team you will have exposure to most aspects of the finance function. The role will include a focus on the reporting budgeting, forecasting and variance analysis at a Group, company, department and product level but will also include an active role in the day to day running of the department and planning; positioning this role as one requiring a more flexible approach with the opportunity to develop.


How to apply

Please send all applications to:

Lucy Christie

Email hr@4dpharmaplc.com

Telephone 01224 900 460

We always welcome applications from talented individuals even if a role is not advertised we would be keen to hear from you. Please send your CV to hr@4dpharmaplc.com

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