Join us

At 4D pharma, we understand that developing a new therapeutic class is challenging. We also understand that our people are our greatest resource – and we look to recruit ambitious and talented individuals from all over the world to be part of this exciting new area of medicine.

Please see our current career opportunities below:


About the Company

4D pharma plc is a pharmaceutical company focused on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drug that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programs in oncology, asthma, IBS and IBD, and a strong pipeline of additional pre-clinical programs in CNS disease, oncology, autoimmunity and inflammation.


Purpose of the Job

Applications are invited for the role of Research Scientist in Neuroscience to join the research team at 4D Pharma Research Ltd in Aberdeen (UK). The successful candidate will provide scientific expertise in assay development for drug discovery using 4D pharma's proprietary MicroRx® platform to identify candidate LPBs for different therapeutic areas. This is mainly focussed on defining suitable properties of LBPs in CNS diseases using appropriate in vitro, in vivo and ex vivo readouts by integrating cellular, molecular, immune and neurological endpoints to study the modulation of the gut-brain axis and support translational development of LBPs. Knowledge of gut-microbiota-brain communication is highly desirable.

Technical requirements for this position include first-hand experience with techniques in cell and tissue culture, animal handling and behaviour, microscopy imaging as well as molecular biology techniques (e.g. transcriptomics), as well as the proven ability to translate these skills into robust and reliable data. The post holder will be expected to personally execute laboratory activities, and to supervise and mentor junior team members in various lab-based activities. We are seeking an individual with a proven ability to develop and undertake high quality research. The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property.


Experience / Qualifications Required

  • MSc. or Ph.D. in Neuroscience or other relevant discipline, ideally with a minimum of 3 years’ experience working in an industrial environment in a similar role
  • Strong background and research training in neuroscience, cellular and molecular biology, immunology, and/or microbiology
  • Experience in designing and performing routine and complex laboratory procedures and assays (in vitro and ex vivo), including molecular, cellular and biochemical techniques in order to understand the in-depth molecular signatures of cellular components of the gut-brain axis in health and disease
  • Interest in exploring mechanisms underlying protein misfolding/spread leading to neurodegeneration in the enteric, peripheral, and central nervous systems to uncover new therapeutic targets
  • Experience in conducting in vivo experiments to study disease pathophysiology from the gut to the brain and validate new targets
  • Personal licence ownership or willingness to acquire licence desirable
  • Expertise in data analysis focusing on one or more neurological disorder (i.e., Parkinson’s disease, Alzheimer’s disease, Stroke, etc.)
  • Proficiency with primary rodent and iPSC human neuronal cell cultures and complex in vitro models is preferred Interest and focus on interdisciplinary work, strong communication and interpersonal skills
  • Excellent analytical, problem-solving, and organisational skills with attention to detail
  • Experience in supervising junior members of staff


Key Areas of Responsibility

  • Assay development and validation for the characterisation of LBPs
  • Analyse data and report results to the Team Leader and other senior members of staff
  • Perform laboratory techniques and protocols according to SOPs
  • Provide scientific expertise to the Discovery (Host) team Keep accurate and detailed records of data
  • Attend and contribute to research group meetings
  • Train junior members of the team


How to apply

Please send all applications to:

Lucy Christie

hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D pharma plc is a pharmaceutical company focused on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drug that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programs in oncology, asthma, IBS and IBD, and a strong pipeline of additional pre-clinical programs in CNS disease, oncology, autoimmunity and inflammation.


Purpose of the Job

The successful candidate will support the activities of the Microbiology team at 4D Pharma Research Ltd in Aberdeen. This will primarily involve applying metabolomics approaches to understand the mode of action of LBP candidates and mining the 4D Pharma bacterial culture collection to identify and characterise microbial metabolites with the potential to mediate host-microbe interactions. This work will include the characterisation of the metabolic profiles of bacterial strains using targeted and untargeted metabolomic analysis tools.

A strong background in a wide range of microbiological techniques is therefore required for this position with a particular emphasis on mass spectrometry, HPLC and other techniques required for the quantification of bacterial metabolites. Previous experience in short-chain fatty acid quantification would be of advantage to this role.


Experience / Qualifications Required

  • MSc in Microbiology, Biochemistry, Biotechnology or a related discipline, with at least a year of academic or industry experience
  • Experience with HPLC and mass spectrometry techniques with experience in HPLC method development
  • Experience with detection, quantification, and purification of bacterial metabolites
  • Previous laboratory experience and ability to follow SOPs
  • Experience in a range of microbiological techniques
  • Experience working with anaerobic bacteria would be advantageous


Key Areas of Responsibility

  • Develop methods to quantify bacterial metabolites
  • Provide technical support to the Microbiology team
  • Keep accurate and detailed records of data
  • Report results to the team lead and research scientists within the team
  • Attend and contribute to research group meetings
  • General laboratory and equipment maintenance and stock control


How to apply

Please send all applications to:

Lucy Christie

hr@4dpharmaplc.com

Telephone 01224 900 460

About the Company

4D pharma plc is a pharmaceutical company focused on developing therapeutics from the human gut microbiome. Live biotherapeutic products (LBPs) derived from the gut microbiome represent a new class of drug that contain live organisms for the prevention, treatment or cure of disease. 4D pharma is a world leader in the LBP field and currently has a number of clinical stage programs in oncology, asthma, IBS and IBD, and a strong pipeline of additional pre-clinical programs in CNS disease, oncology, autoimmunity and inflammation.


Purpose of the Job

We have an exciting role for a self-motivated and experienced Financial Controller reporting to the VP of Finance. You will be proactive in the management of the business, being responsible for upholding and developing it’s reporting and controls to ensure the smooth running of the finances. Working in an international group as a senior member of a small team, your responsibilities will traverse all aspects of the Finance function and will require a candidate with a broad understanding of financial processes and controls, reporting, and excellent communication skills. The role is suited to an individual with experience that demonstrates excellent time management, attention to detail and organization skills in an interesting, complex and unique environment.


Experience and Qualifications

  • ACCA/ACA/CIMA finalist or qualified, practice background preferred
  • Advanced knowledge of Excel
  • A good working knowledge of other Microsoft applications, prior usage of Microsoft Business Central (formerly Navision) and experience in systems implementation is preferred but not required
  • A sound understanding of the interaction between statutory reporting requirements, group consolidations and various taxes, systems and controls
  • Monthly management accounting and year end statutory accounts experience, and an ability to put together complete sets of accounts and working papers
  • Ability to communicate key financial information to non-finance personnel in a clear and concise way
  • Ability to build strong professional relationships with colleagues across different teams and functions
  • Understanding of data and execution of implementation plans
  • Strong attention to detail
  • Self-starter with the ability to identify problems, find solutions and to work independently.
  • Good analytical, planning and organizational skills


Areas of responsibility include

  • Responsibility for the monthly management accounts, ensuring they are completed to deadlines and in accordance with adopted policies and procedures
  • Produce commentaries for the variances to budget
  • Monthly sign off balance sheet reconciliations
  • Manage the purchase invoice system, including purchase ordering, invoice posting and payment processes
  • Assistance with quarterly and year end audited results for NASDAQ, AIM and other regulatory agencies
  • Management of, and improvements to, internal controls
  • Implementation and configuration of new finance systems
  • Assistance with supplier management and contract compliance
  • Liaison with external stakeholders like auditors, banks, and suppliers
  • Assistance with the management of the Finance team
  • Ability to create business models in Excel, for both external and internal reporting
  • Assistance with, and management of, budgets and forecasts
  • Ensure VAT, corporation tax, employers taxes and other regulatory requirements are suitably controlled and met on time
  • Ad hoc work as required, e.g. year-end audit analysis
  • Proactively identify areas for improvement and contribute towards a culture of continuous improvement


How to apply

Please send all applications to:

Email hr@4dpharmaplc.com

Telephone 01224 900 460

We always welcome applications from talented individuals even if a role is not advertised we would be keen to hear from you. Please send your CV to hr@4dpharmaplc.com

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