Join us

At 4D pharma, we understand that developing a new therapeutic class is challenging. We also understand that our people are our greatest resource – and we look to recruit ambitious and talented individuals from all over the world to be part of this exciting new area of medicine.

Please see our current career opportunities below:

Purpose of the Job

This is an opportunity to build and manage the clinical operations function with overall accountability for the management and execution for clinical trials on a global basis across the company's portfolio. The candidate will be based in the company headquarters in Leeds and work within the clinical team, working with various CROs and the regulatory team to ensure compliant and successful clinical trials.

Key Areas of Responsibility

  • Responsible for the operational management of multiple clinical trials across multiple sites
  • Matrix management of multi-disciplinary trial team, to ensure all deliverables are me
  • Manage all operational elements of the clinical trial from set-up through execution and completion
  • Taking responsibility for the selection and management of CROs
  • Hiring and managing a team of CRAs and CTAs
  • Identify and track critical path/activities and risks, develop contingency and alternative plans and provide regular updates
  • Initiate, and oversee execution of the clinical trials, working with multiple internal teams and contractors, managing timelines, resource, budgets and risks and reporting on project progress
  • Managing timelines, resource, budgets and risks and reporting on progress
  • Work closely with the Project Management function to ensure smooth overall study execution

Experience / Qualifications Required

  • Bachelor’s degree, preferably in science or health-related field
  • At least 6 years’ experience managing clinical trials from Phase I through regulatory approval in a commercial setting
  • Previous line management experience
  • Previous experience with CRO management
  • Excellent working knowledge of clinical trial legislation including GCP, standards and regulations
  • Ability to work effectively and independently to fast-moving timelines within a fast-paced working environment
  • Strong influencing skills
  • A collaborative nature

How to Apply

Please send all applications to hr@4dpharmaplc.com with your covering letter and CV.

Purpose of the Job

Applications are invited for the role of Senior Immunologist (Team Leader) to join the research team at 4D Pharma Research Ltd in Aberdeen (UK). The successful candidate will provide scientific expertise and leadership to the proprietary MicroRx platform, investigating microbe characteristics and host responses of LPBs progressing to the clinic. This is mainly focussed on defining mechanism of action of selected LBPs in novel disease areas using appropriate preclinical models and readouts. The role will require proven expertise in a range of immunological techniques, especially in investigating immune-mediated mechanisms in preclinical models of disease, and the proven ability to translate these skills into robust and reliable data. The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property.

Experience / Qualifications Required

  • A PhD with relevant post-doctoral or industry experience (>3-4 years) in immunology or a related discipline
  • Solid experience in a range of in vitro and in vivo immunology techniques and proven expertise in immunological assay development
  • Experience with investigating immune-mediated mechanisms in translational disease models
  • Ideally a Home Office personal/project licence holder (or equivalent)
  • Thorough understanding of the gut microbiome and host-microbe interactions
  • Highly motivated and innovative with the ability to work independently and integrate into a multidisciplinary team of microbiologists and molecular biologists
  • Good organisational and communication skills proven by previous line management and supervision experience

How to Apply

Please send all applications to hr@4dpharmaplc.com with your covering letter and CV.

Purpose of the Job

Applications are invited for the role of Senior Microbiologist (Team Leader) to join the research team at 4D Pharma Research Ltd in Aberdeen (UK). The successful candidate will provide scientific expertise and leadership to the proprietary MicroRx platform, for the early discovery of new LBPs in novel therapeutic areas. The successful candidate will investigate the mechanisms through which bacterial candidates confer disease protection on the host. This involves mining of the 4D bacterial culture collection for identification of microbial molecules and pathways important for host interaction. An extensive knowledge of host-microbe communication, ideally in the field of gut microbiome research, is therefore crucial to this position. A background in metabolomics/proteomics is highly desirable along with proven expertise in microbial genetics. The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property.

Experience / Qualifications Required

  • A PhD with relevant post-doctoral or industry experience (>3-4 years) in microbiology or a related discipline
  • Solid experience in a range of (anaerobic) microbiological techniques and proven expertise in assay development
  • Experience with bacterial protein purification, analysis of bacterial metabolites and genome mining
  • Thorough understanding of the gut microbiome and host-microbe interactions
  • Highly motivated and innovative with the ability to work independently and integrate into a multidisciplinary team of microbiologists and molecular biologists
  • Good organisational and communication skills proven by previous line management and supervision experience

How to Apply

Please send all applications to hr@4dpharmaplc.com with your covering letter and CV.

Purpose of the Job

Applications are invited for the role of Scientist (Discovery I Team) to join the research team at 4D Pharma Research Ltd in Aberdeen (UK). The successful candidate will provide scientific expertise to the proprietary MicroRx platform, investigating microbe characteristics and host responses of LPBs progressing to the clinic. This is mainly focussed on developing and validating cell-based screening assays for LBPs in novel disease areas. The role will require proven expertise in a range of biological and immunological techniques, and the proven ability to translate these skills into robust and reliable screening assays and data analysis. The post-holder will have the opportunity to engage in the wider research activities of the 4D Pharma Research team, write up results in the form of reports and publications, present research outcomes at meetings, and generate intellectual property.

Experience / Qualifications Required

  • A PhD with relevant post-doctoral or industry experience (>3-4 years) in cell biology, immunology or a related discipline
  • Solid experience in a range of in vitro and in vivo techniques and proven expertise in assay development (primary cell culture, co-culture systems, multiparameter flow cytometry, multiplex assays, confocal microscopy, signalling pathway analysis and qPCR)
  • Thorough understanding of the gut microbiome and host-microbe interactions
  • Highly motivated and innovative with the ability to work independently and integrate into a multidisciplinary team of microbiologists and cell biologists
  • Good organisational and communication skills

How to Apply

Please send all applications to hr@4dpharmaplc.com with your covering letter and CV.

Purpose of the Job

The successful candidate will be responsible for the processing of pre-clinical samples for the purpose of transcriptomic analyses. In addition, they will support the wider activities of the molecular microbiology team in 4D Pharma Research Ltd. Previous relevant experience is essential to this position as is the ability to record data with a high level of accuracy.

Experience / Qualifications Required

  • This position has a minimum requirement of a BSc. degree in genetics, molecular biology or microbiology with at least 1 year’s relevant experience in the research area
  • Experience of performing nucleic acid extractions from a variety of cell types (bacterial and mammalian)
  • Competency in performing qPCR and RT-qPCR assays
  • Impeccable aseptic technique
  • Experience in bacterial culturing techniques
  • Previous laboratory experience and ability to follow SOPs
  • Basic bioinformatics skills would be advantageous

Key Areas of Responsibility

  • Extraction and analysis of nucleic acids from pre-clinical samples
  • Optimising and performing qPCR and RT-qPCR assays
  • Provide technical support to the wider molecular microbiology team
  • Keep accurate and detailed records of data
  • Reporting of results to the to the molecular microbiology team leader
  • Attend and contribute to research group meetings
  • General laboratory maintenance and stock control

How to Apply

Please send all applications to hr@4dpharmaplc.com with your CV and covering letter.

Purpose of the Job

The successful candidate will provide technical support to the activities of the Discovery I Microbe team in 4D Pharma Research Ltd. The primary focus of the group is to screen candidate LBPs for translation into pre-clinical disease models. The candidate will be responsible for supporting the team in performing screening assays. Previous practical experience in microbiology and excellent aseptic technique are essential.

Experience / Qualifications Required

  • This position has a minimum requirement of a HND in biochemistry, biology, microbiological or biomedical sciences or relevant experience
  • Competency in a variety of microbiological laboratory techniques
  • Experience with bacterial culturing techniques, including strict anaerobes would be advantageous

Key Areas of Responsibility

  • Contribute / write relevant SOPs and risk assessments
  • Provide technical support to the wider 4D Pharma team
  • Keep accurate and detailed records of data
  • Reporting of results to the microbe team
  • Perform laboratory techniques and protocols
  • Attend and contribute to research group meetings.

How to Apply

Please send all applications to hr@4dpharmaplc.com with your covering letter and CV.

Purpose of the Job

We have an excellent career opportunity for an experienced, hard-working and committed IT Engineer to implement the IT documentation system (eDMS) for an exciting pharmaceutical company. The candidate will be required to provide a full support for the Company’s electronic documentation system throughout the various sites. The role will be based in Spain, ideally in Leon. Travels in all sites are planned.

Experience / Qualifications Required

  • Masters degree in IT
  • At least 3 years’ experience working on a GAMP 5 accredited electronic QMS within the pharmaceutical industry
  • An experience under FDA 21 CFR Part 11 environment would be appreciated
  • Knowledge in various electronic pharmaceutical systems, such as LIMS, ERP, Master control
  • Ability to work effectively and independently to fast-moving timelines within a fast-paced working environment

Key Areas of Responsibility

  • Maintenance and support of the IT Company’s concerning Documentation management system : Support the implementation and administration of the IT documentation system, specific maintenance of the system, perform site visits, offer users appropriate support and advice
  • Scheduling upgrades and security backups of the IT documentation, securing data from internal and external attack;
  • Lead IT documentation system continual improvement: implementation of new modules (QMS – Quality Management System- and other for clinical trial purposes and regulatory submissions), update existed modules (Documentation) in order to answer better of the user needs. Perform IT documentation system audit (with action plan to assess compliance and effectiveness of the IT documentation management)
  • Compile and write IT documents support & train users
  • Implement other IT system (LIMS, ERP, CTMs,) and develop interface with the current documentation System (QMS)
  • Develop the “0 Paper” on manufacturing site. Perform other related duties as assigned by the Quality Director and Global Project Manager

Reporting / Working Relationships

  • Reports to the Quality Director and Global Project Manager
  • Liaises with the quality & development team
  • Part of the quality team

How to Apply

Please send all applications to hr@4dpharmaplc.com with your covering letter and CV.

Purpose of the Job

This is a full-time position to process human samples (including faeces and urine) for microbiome and metabolomic analysis. The appointee will liaise with the research team to advance various programmes of the company.

Experience / Qualifications Required

  • An MSc. in i.e. genetics microbiology, biochemistry or relevant biological science or a BSc with at least 1 year’s relevant experience in the research area
  • Good report writing and presentation skills
  • Previous laboratory experience and ability to follow SOPs
  • Good analytical and computer skills
  • Capability of working effectively within a team to achieve results
  • Evidence of excellent organisational and communication skills
  • Vaccination appropriate for handling biological samples of human origin
  • Experience in 16S rRNA amplification, purification and sequencing for microbiome compositional analysis
  • Please note that Garda vetting and international police clearance check may form part of the selection process

How to Apply

Candidates should submit a curriculum vitae along with a covering letter to the following email address: corkrecruitment@4dpharmaplc.com to arrive no later than Friday 6th October. For any queries or further information on the post please contact Dr Eileen O’Herlihy (eoh@4dpharmaplc.com).

We always welcome applications from talented individuals even if a role is not advertised we would be keen to hear from you. Please send your CV to hr@4dpharmaplc.com

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